| 000 | 02691 a2200817 4500 | ||
|---|---|---|---|
| 005 | 20250517170446.0 | ||
| 264 | 0 | _c20171002 | |
| 008 | 201710s 0 0 eng d | ||
| 022 | _a1546-170X | ||
| 024 | 7 |
_a10.1038/nm.4379 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aZhang, Pingzhao | |
| 245 | 0 | 0 |
_aIntrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation. _h[electronic resource] |
| 260 |
_bNature medicine _cSep 2017 |
||
| 300 |
_a1055-1062 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAzepines _xpharmacology |
| 650 | 0 | 4 | _aBlotting, Western |
| 650 | 0 | 4 | _aCell Cycle Proteins |
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 | _aCell Survival |
| 650 | 0 | 4 | _aDrug Resistance, Neoplasm |
| 650 | 0 | 4 | _aGene Expression Profiling |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aImmunoprecipitation |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMechanistic Target of Rapamycin Complex 1 |
| 650 | 0 | 4 | _aMolecular Targeted Therapy |
| 650 | 0 | 4 |
_aMultiprotein Complexes _xdrug effects |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aNuclear Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aProstatic Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aProteasome Endopeptidase Complex _xdrug effects |
| 650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-akt _xdrug effects |
| 650 | 0 | 4 |
_aRNA-Binding Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aRepressor Proteins _xgenetics |
| 650 | 0 | 4 | _aReverse Transcriptase Polymerase Chain Reaction |
| 650 | 0 | 4 |
_aTOR Serine-Threonine Kinases _xdrug effects |
| 650 | 0 | 4 |
_aTranscription Factors _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aTriazoles _xpharmacology |
| 650 | 0 | 4 |
_arac1 GTP-Binding Protein _xgenetics |
| 700 | 1 | _aWang, Dejie | |
| 700 | 1 | _aZhao, Yu | |
| 700 | 1 | _aRen, Shancheng | |
| 700 | 1 | _aGao, Kun | |
| 700 | 1 | _aYe, Zhenqing | |
| 700 | 1 | _aWang, Shangqian | |
| 700 | 1 | _aPan, Chun-Wu | |
| 700 | 1 | _aZhu, Yasheng | |
| 700 | 1 | _aYan, Yuqian | |
| 700 | 1 | _aYang, Yinhui | |
| 700 | 1 | _aWu, Di | |
| 700 | 1 | _aHe, Yundong | |
| 700 | 1 | _aZhang, Jun | |
| 700 | 1 | _aLu, Daru | |
| 700 | 1 | _aLiu, Xiuping | |
| 700 | 1 | _aYu, Long | |
| 700 | 1 | _aZhao, Shimin | |
| 700 | 1 | _aLi, Yao | |
| 700 | 1 | _aLin, Dong | |
| 700 | 1 | _aWang, Yuzhuo | |
| 700 | 1 | _aWang, Liguo | |
| 700 | 1 | _aChen, Yu | |
| 700 | 1 | _aSun, Yinghao | |
| 700 | 1 | _aWang, Chenji | |
| 700 | 1 | _aHuang, Haojie | |
| 773 | 0 |
_tNature medicine _gvol. 23 _gno. 9 _gp. 1055-1062 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/nm.4379 _zAvailable from publisher's website |
| 999 |
_c27463298 _d27463298 |
||