000 01986 a2200577 4500
005 20250517170415.0
264 0 _c20180514
008 201805s 0 0 eng d
022 _a1875-9777
024 7 _a10.1016/j.stem.2017.07.009
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aThomas, Charles A
245 0 0 _aModeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.
_h[electronic resource]
260 _bCell stem cell
_c09 2017
300 _a319-331.e8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAstrocytes
_xdrug effects
650 0 4 _aAutoimmune Diseases
_xenzymology
650 0 4 _aBase Sequence
650 0 4 _aCell Extracts
650 0 4 _aChild
650 0 4 _aCytosol
_xmetabolism
650 0 4 _aDNA
_xmetabolism
650 0 4 _aExodeoxyribonucleases
_xdeficiency
650 0 4 _aHumans
650 0 4 _aInfant
650 0 4 _aInfant, Newborn
650 0 4 _aInflammation
_xpathology
650 0 4 _aInterferons
_xpharmacology
650 0 4 _aLong Interspersed Nucleotide Elements
_xgenetics
650 0 4 _aMale
650 0 4 _aMicrocephaly
_xpathology
650 0 4 _aNervous System
_xpathology
650 0 4 _aNeural Stem Cells
_xmetabolism
650 0 4 _aNeurons
_xdrug effects
650 0 4 _aOrganoids
_xmetabolism
650 0 4 _aPhenotype
650 0 4 _aPhosphoproteins
_xdeficiency
650 0 4 _aStem Cells
_xdrug effects
650 0 4 _aUp-Regulation
_xdrug effects
700 1 _aTejwani, Leon
700 1 _aTrujillo, Cleber A
700 1 _aNegraes, Priscilla D
700 1 _aHerai, Roberto H
700 1 _aMesci, Pinar
700 1 _aMacia, Angela
700 1 _aCrow, Yanick J
700 1 _aMuotri, Alysson R
773 0 _tCell stem cell
_gvol. 21
_gno. 3
_gp. 319-331.e8
856 4 0 _uhttps://doi.org/10.1016/j.stem.2017.07.009
_zAvailable from publisher's website
999 _c27461415
_d27461415