000 01434 a2200361 4500
005 20250517165215.0
264 0 _c20180518
008 201805s 0 0 eng d
022 _a1950-6007
024 7 _a10.1016/j.biopha.2017.07.101
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMahmoud, Ayman M
245 0 0 _aBerberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats.
_h[electronic resource]
260 _bBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
_cOct 2017
300 _a280-291 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBerberine
_xtherapeutic use
650 0 4 _aChemical and Drug Induced Liver Injury
_xmetabolism
650 0 4 _aHeme Oxygenase (Decyclizing)
_xmetabolism
650 0 4 _aMale
650 0 4 _aMethotrexate
_xtoxicity
650 0 4 _aNF-E2-Related Factor 2
_xmetabolism
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aPPAR gamma
_xmetabolism
650 0 4 _aRats, Wistar
650 0 4 _aSignal Transduction
700 1 _aHozayen, Walaa G
700 1 _aRamadan, Shimaa M
773 0 _tBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
_gvol. 94
_gp. 280-291
856 4 0 _uhttps://doi.org/10.1016/j.biopha.2017.07.101
_zAvailable from publisher's website
999 _c27422132
_d27422132