000			02267 a2200649 4500
005			20250517163714.0
264		0	_c20170905
008			201709s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/acs.jmedchem.7b00076 _2doi
040			_aNLM _beng _cNLM
100	1		_aZhu, Wei
245	0	0	_aDesign, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer. _h[electronic resource]
260			_bJournal of medicinal chemistry _c07 2017
300			_a6018-6035 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAminopyridines _xchemical synthesis
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xchemical synthesis
650	0	4	_aCarcinoma, Non-Small-Cell Lung _xdrug therapy
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDatabases, Chemical
650	0	4	_aDrug Design
650	0	4	_aDrug Screening Assays, Antitumor
650	0	4	_aFemale
650	0	4	_aHeterografts
650	0	4	_aHumans
650	0	4	_aIndazoles _xchemical synthesis
650	0	4	_aLung Neoplasms _xdrug therapy
650	0	4	_aMice
650	0	4	_aMice, Nude
650	0	4	_aMolecular Docking Simulation
650	0	4	_aNeoplasm Transplantation
650	0	4	_aPhosphorylation
650	0	4	_aProtein Kinase Inhibitors _xchemical synthesis
650	0	4	_aProtein-Tyrosine Kinases _xantagonists & inhibitors
650	0	4	_aPyridines _xchemical synthesis
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aSignal Transduction
650	0	4	_aStereoisomerism
650	0	4	_aStructure-Activity Relationship
700	1		_aChen, Hui
700	1		_aWang, Yulan
700	1		_aWang, Jiang
700	1		_aPeng, Xia
700	1		_aChen, Xianjie
700	1		_aGao, Yinglei
700	1		_aLi, Chunpu
700	1		_aHe, Yulong
700	1		_aAi, Jing
700	1		_aGeng, Meiyu
700	1		_aZheng, Mingyue
700	1		_aLiu, Hong
773	0		_tJournal of medicinal chemistry _gvol. 60 _gno. 14 _gp. 6018-6035
856	4	0	_uhttps://doi.org/10.1021/acs.jmedchem.7b00076 _zAvailable from publisher's website
999			_c27374532 _d27374532