000 01446 a2200409 4500
005 20250517163054.0
264 0 _c20171120
008 201711s 0 0 eng d
022 _a1476-5594
024 7 _a10.1038/onc.2017.224
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTrinidad, A G
245 0 0 _aPyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.
_h[electronic resource]
260 _bOncogene
_c11 2017
300 _a6164-6176 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aCell Cycle
_xgenetics
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xgenetics
650 0 4 _aColorectal Neoplasms
_xgenetics
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aGene Knockdown Techniques
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xgenetics
650 0 4 _aMutation
650 0 4 _aProtein Kinases
_xgenetics
650 0 4 _aProto-Oncogene Proteins p21(ras)
_xgenetics
650 0 4 _aSignal Transduction
_xgenetics
700 1 _aWhalley, N
700 1 _aRowlinson, R
700 1 _aDelpuech, O
700 1 _aDudley, P
700 1 _aRooney, C
700 1 _aCritchlow, S E
773 0 _tOncogene
_gvol. 36
_gno. 44
_gp. 6164-6176
856 4 0 _uhttps://doi.org/10.1038/onc.2017.224
_zAvailable from publisher's website
999 _c27352558
_d27352558