000 01866 a2200529 4500
005 20250517162010.0
264 0 _c20180618
008 201806s 0 0 eng d
022 _a1557-3125
024 7 _a10.1158/1541-7786.MCR-17-0211
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aEmery, Caroline M
245 0 0 _aBRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity.
_h[electronic resource]
260 _bMolecular cancer research : MCR
_c10 2017
300 _a1431-1444 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAllosteric Site
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
650 0 4 _aColorectal Neoplasms
_xdrug therapy
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aMAP Kinase Kinase 1
_xchemistry
650 0 4 _aMAP Kinase Kinase 2
_xchemistry
650 0 4 _aMAP Kinase Signaling System
_xdrug effects
650 0 4 _aModels, Molecular
650 0 4 _aMutation
650 0 4 _aPhosphorylation
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProtein Structure, Secondary
650 0 4 _aProto-Oncogene Proteins B-raf
_xchemistry
650 0 4 _araf Kinases
_xmetabolism
700 1 _aMonaco, Kelli-Ann
700 1 _aWang, Ping
700 1 _aBalak, Marissa
700 1 _aFreeman, Alyson
700 1 _aMeltzer, Jodi
700 1 _aDelach, Scott M
700 1 _aRakiec, Daniel
700 1 _aRuddy, David A
700 1 _aKorn, Joshua M
700 1 _aHaling, Jacob
700 1 _aAcker, Michael G
700 1 _aCaponigro, Giordano
773 0 _tMolecular cancer research : MCR
_gvol. 15
_gno. 10
_gp. 1431-1444
856 4 0 _uhttps://doi.org/10.1158/1541-7786.MCR-17-0211
_zAvailable from publisher's website
999 _c27317407
_d27317407