000			01916 a2200565 4500
005			20250517161230.0
264		0	_c20170925
008			201709s 0 0 eng d
022			_a1528-0020
024	7		_a10.1182/blood-2016-11-752840 _2doi
040			_aNLM _beng _cNLM
100	1		_aMachlus, Kellie R
245	0	0	_aSelinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis. _h[electronic resource]
260			_bBlood _c08 2017
300			_a1132-1143 p. _bdigital
500			_aPublication Type: Clinical Trial, Phase I; Journal Article
650	0	4	_aAnimals
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aBlood Platelets _xdrug effects
650	0	4	_aBone Marrow _xdrug effects
650	0	4	_aCell Count
650	0	4	_aCell Differentiation _xdrug effects
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aFetus _xpathology
650	0	4	_aHydrazines _xadverse effects
650	0	4	_aLiver _xembryology
650	0	4	_aMegakaryocytes _xdrug effects
650	0	4	_aMice, Knockout
650	0	4	_aPlatelet Activation _xdrug effects
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aStem Cells _xcytology
650	0	4	_aThrombocytopenia _xblood
650	0	4	_aThrombopoiesis _xdrug effects
650	0	4	_aThrombopoietin _xmetabolism
650	0	4	_aTriazoles _xadverse effects
700	1		_aWu, Stephen K
700	1		_aVijey, Prakrith
700	1		_aSoussou, Thomas S
700	1		_aLiu, Zhi-Jian
700	1		_aShacham, Eran
700	1		_aUnger, T J
700	1		_aKashyap, Trinayan
700	1		_aKlebanov, Boris
700	1		_aSola-Visner, Martha
700	1		_aCrochiere, Marsha
700	1		_aItaliano, Joseph E
700	1		_aLandesman, Yosef
773	0		_tBlood _gvol. 130 _gno. 9 _gp. 1132-1143
856	4	0	_uhttps://doi.org/10.1182/blood-2016-11-752840 _zAvailable from publisher's website
999			_c27292633 _d27292633