| 000 | 01699 a2200469 4500 | ||
|---|---|---|---|
| 005 | 20250517161113.0 | ||
| 264 | 0 | _c20171121 | |
| 008 | 201711s 0 0 eng d | ||
| 022 | _a1464-3391 | ||
| 024 | 7 |
_a10.1016/j.bmc.2017.06.002 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aYoon, Suyoung | |
| 245 | 0 | 0 |
_aDiscovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry _c08 2017 |
||
| 300 |
_a4145-4152 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aCell Line, Tumor |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aHEK293 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLeucine-tRNA Ligase _xmetabolism |
| 650 | 0 | 4 |
_aMass Spectrometry _xmethods |
| 650 | 0 | 4 |
_aMechanistic Target of Rapamycin Complex 1 _xantagonists & inhibitors |
| 650 | 0 | 4 | _aPhosphorylation |
| 650 | 0 | 4 | _aProton Magnetic Resonance Spectroscopy |
| 650 | 0 | 4 |
_aRibosomal Protein S6 Kinases _xmetabolism |
| 650 | 0 | 4 |
_aSulfonic Acids _xchemistry |
| 700 | 1 | _aKim, Jong Hyun | |
| 700 | 1 | _aKoh, Yura | |
| 700 | 1 | _aTran, Phuong-Thao | |
| 700 | 1 | _aAnn, Jihyae | |
| 700 | 1 | _aYoon, Ina | |
| 700 | 1 | _aJang, Jayun | |
| 700 | 1 | _aKim, Won Kyung | |
| 700 | 1 | _aLee, Sangkook | |
| 700 | 1 | _aLee, Jiyoun | |
| 700 | 1 | _aKim, Sunghoon | |
| 700 | 1 | _aLee, Jeewoo | |
| 773 | 0 |
_tBioorganic & medicinal chemistry _gvol. 25 _gno. 15 _gp. 4145-4152 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmc.2017.06.002 _zAvailable from publisher's website |
| 999 |
_c27288284 _d27288284 |
||