000 | 02376 a2200661 4500 | ||
---|---|---|---|
005 | 20250517160054.0 | ||
264 | 0 | _c20180521 | |
008 | 201805s 0 0 eng d | ||
022 | _a1549-490X | ||
024 | 7 |
_a10.1634/theoncologist.2017-0175 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aLieu, Christopher H | |
245 | 0 | 0 |
_aA Phase Ib Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Cobimetinib and Duligotuzumab in Patients with Previously Treated Locally Advanced or Metastatic Cancers with Mutant KRAS. _h[electronic resource] |
260 |
_bThe oncologist _c09 2017 |
||
300 |
_a1024-e89 p. _bdigital |
||
500 | _aPublication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study | ||
650 | 0 | 4 |
_aAcneiform Eruptions _xepidemiology |
650 | 0 | 4 | _aAdministration, Oral |
650 | 0 | 4 | _aAdult |
650 | 0 | 4 | _aAged |
650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xpharmacology |
650 | 0 | 4 |
_aAsthenia _xepidemiology |
650 | 0 | 4 |
_aAzetidines _xpharmacology |
650 | 0 | 4 |
_aColorectal Neoplasms _xdrug therapy |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 |
_aDrug Eruptions _xepidemiology |
650 | 0 | 4 |
_aErbB Receptors _xantagonists & inhibitors |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aHypokalemia _xepidemiology |
650 | 0 | 4 |
_aImmunoglobulin G _xpharmacology |
650 | 0 | 4 |
_aMAP Kinase Kinase 1 _xantagonists & inhibitors |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMiddle Aged |
650 | 0 | 4 | _aNeoplasm Staging |
650 | 0 | 4 |
_aPiperidines _xpharmacology |
650 | 0 | 4 | _aProspective Studies |
650 | 0 | 4 |
_aProto-Oncogene Proteins p21(ras) _xgenetics |
650 | 0 | 4 |
_aReceptor, ErbB-3 _xantagonists & inhibitors |
650 | 0 | 4 |
_aSignal Transduction _xdrug effects |
650 | 0 | 4 | _aTreatment Outcome |
700 | 1 | _aHidalgo, Manuel | |
700 | 1 | _aBerlin, Jordan D | |
700 | 1 | _aKo, Andrew H | |
700 | 1 | _aCervantes, Andres | |
700 | 1 | _aLoRusso, Patricia | |
700 | 1 | _aGerber, David E | |
700 | 1 | _aEder, J Paul | |
700 | 1 | _aEckhardt, S Gail | |
700 | 1 | _aKapp, Amy V | |
700 | 1 | _aTsuhako, Amy | |
700 | 1 | _aMcCall, Bruce | |
700 | 1 | _aPirzkall, Andrea | |
700 | 1 | _aUyei, Anne | |
700 | 1 | _aTabernero, Josep | |
773 | 0 |
_tThe oncologist _gvol. 22 _gno. 9 _gp. 1024-e89 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1634/theoncologist.2017-0175 _zAvailable from publisher's website |
999 |
_c27256616 _d27256616 |