000 01945 a2200577 4500
005 20250517155700.0
264 0 _c20170822
008 201708s 0 0 eng d
022 _a1533-4406
024 7 _a10.1056/NEJMoa1706450
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aRobson, Mark
245 0 0 _aOlaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation.
_h[electronic resource]
260 _bThe New England journal of medicine
_c08 2017
300 _a523-533 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAntineoplastic Agents
_xadverse effects
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aChemotherapy, Adjuvant
650 0 4 _aDisease-Free Survival
650 0 4 _aFemale
650 0 4 _aGenes, BRCA1
650 0 4 _aGenes, BRCA2
650 0 4 _aGerm-Line Mutation
650 0 4 _aHumans
650 0 4 _aKaplan-Meier Estimate
650 0 4 _aMiddle Aged
650 0 4 _aNeoplasm Metastasis
_xdrug therapy
650 0 4 _aPhthalazines
_xadverse effects
650 0 4 _aPiperazines
_xadverse effects
650 0 4 _aPoly(ADP-ribose) Polymerase Inhibitors
_xadverse effects
650 0 4 _aReceptor, ErbB-2
650 0 4 _aYoung Adult
700 1 _aIm, Seock-Ah
700 1 _aSenkus, Elżbieta
700 1 _aXu, Binghe
700 1 _aDomchek, Susan M
700 1 _aMasuda, Norikazu
700 1 _aDelaloge, Suzette
700 1 _aLi, Wei
700 1 _aTung, Nadine
700 1 _aArmstrong, Anne
700 1 _aWu, Wenting
700 1 _aGoessl, Carsten
700 1 _aRunswick, Sarah
700 1 _aConte, Pierfranco
773 0 _tThe New England journal of medicine
_gvol. 377
_gno. 6
_gp. 523-533
856 4 0 _uhttps://doi.org/10.1056/NEJMoa1706450
_zAvailable from publisher's website
999 _c27243196
_d27243196