000 02284 a2200613 4500
005 20250517155656.0
264 0 _c20181218
008 201812s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/s41598-017-03027-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSagar, Divya
245 0 0 _aAntibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity.
_h[electronic resource]
260 _bScientific reports
_c06 2017
300 _a2707 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntibodies, Blocking
_xpharmacology
650 0 4 _aCentral Nervous System
_ximmunology
650 0 4 _aChemokine CCL2
_xmetabolism
650 0 4 _aDendritic Cells
_xdrug effects
650 0 4 _aEncephalomyelitis, Autoimmune, Experimental
_xdiagnosis
650 0 4 _aEndothelium, Vascular
_xmetabolism
650 0 4 _aImmunity
_xdrug effects
650 0 4 _aLectins
_xgenetics
650 0 4 _aLectins, C-Type
_xantagonists & inhibitors
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aModels, Biological
650 0 4 _aMyeloid Cells
_xdrug effects
650 0 4 _aPhenotype
650 0 4 _aProtein Binding
650 0 4 _aProtein Tyrosine Phosphatase, Non-Receptor Type 11
_xmetabolism
650 0 4 _aProtein Tyrosine Phosphatase, Non-Receptor Type 6
_xmetabolism
650 0 4 _aReceptors, Mitogen
_xantagonists & inhibitors
650 0 4 _aRecurrence
650 0 4 _aSeverity of Illness Index
650 0 4 _aSignal Transduction
650 0 4 _aTransendothelial and Transepithelial Migration
700 1 _aSingh, Narendra P
700 1 _aGinwala, Rashida
700 1 _aHuang, Xiaofang
700 1 _aPhilip, Ramila
700 1 _aNagarkatti, Mitzi
700 1 _aNagarkatti, Prakash
700 1 _aNeumann, Konstantin
700 1 _aRuland, Jürgen
700 1 _aAndrews, Allison M
700 1 _aRamirez, Servio H
700 1 _aKhan, Zafar K
700 1 _aJain, Pooja
773 0 _tScientific reports
_gvol. 7
_gno. 1
_gp. 2707
856 4 0 _uhttps://doi.org/10.1038/s41598-017-03027-x
_zAvailable from publisher's website
999 _c27242990
_d27242990