000			02088 a2200637 4500
005			20250517154326.0
264		0	_c20170911
008			201709s 0 0 eng d
022			_a1546-170X
024	7		_a10.1038/nm.4345 _2doi
040			_aNLM _beng _cNLM
100	1		_aWu, Hao
245	0	0	_aMetformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. _h[electronic resource]
260			_bNature medicine _cJul 2017
300			_a850-858 p. _bdigital
500			_aPublication Type: Journal Article; Randomized Controlled Trial
650	0	4	_aAnimals
650	0	4	_aBile Acids and Salts _xmetabolism
650	0	4	_aDNA, Bacterial _xanalysis
650	0	4	_aDiabetes Mellitus, Type 2 _xdrug therapy
650	0	4	_aDouble-Blind Method
650	0	4	_aFatty Acids, Volatile _xmetabolism
650	0	4	_aFecal Microbiota Transplantation
650	0	4	_aFeces _xchemistry
650	0	4	_aFemale
650	0	4	_aGastrointestinal Microbiome _xgenetics
650	0	4	_aGerm-Free Life
650	0	4	_aGlucose Tolerance Test
650	0	4	_aHumans
650	0	4	_aHypoglycemic Agents _xtherapeutic use
650	0	4	_aIn Vitro Techniques
650	0	4	_aMale
650	0	4	_aMetagenomics
650	0	4	_aMetformin _xtherapeutic use
650	0	4	_aMice
650	0	4	_aMiddle Aged
700	1		_aEsteve, Eduardo
700	1		_aTremaroli, Valentina
700	1		_aKhan, Muhammad Tanweer
700	1		_aCaesar, Robert
700	1		_aMannerås-Holm, Louise
700	1		_aStåhlman, Marcus
700	1		_aOlsson, Lisa M
700	1		_aSerino, Matteo
700	1		_aPlanas-Fèlix, Mercè
700	1		_aXifra, Gemma
700	1		_aMercader, Josep M
700	1		_aTorrents, David
700	1		_aBurcelin, Rémy
700	1		_aRicart, Wifredo
700	1		_aPerkins, Rosie
700	1		_aFernàndez-Real, José Manuel
700	1		_aBäckhed, Fredrik
773	0		_tNature medicine _gvol. 23 _gno. 7 _gp. 850-858
856	4	0	_uhttps://doi.org/10.1038/nm.4345 _zAvailable from publisher's website
999			_c27197173 _d27197173