000 | 01898 a2200589 4500 | ||
---|---|---|---|
005 | 20250517153427.0 | ||
264 | 0 | _c20180406 | |
008 | 201804s 0 0 eng d | ||
022 | _a1949-2553 | ||
024 | 7 |
_a10.18632/oncotarget.17464 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aZheng, Mengzhu | |
245 | 0 | 0 |
_aStructure based discovery of clomifene as a potent inhibitor of cancer-associated mutant IDH1. _h[electronic resource] |
260 |
_bOncotarget _cJul 2017 |
||
300 |
_a44255-44265 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntineoplastic Agents _xchemistry |
650 | 0 | 4 | _aBinding Sites |
650 | 0 | 4 | _aBiomarkers, Tumor |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
650 | 0 | 4 |
_aClomiphene _xchemistry |
650 | 0 | 4 |
_aEnzyme Activation _xdrug effects |
650 | 0 | 4 |
_aEnzyme Inhibitors _xchemistry |
650 | 0 | 4 | _aGene Knockdown Techniques |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aInhibitory Concentration 50 |
650 | 0 | 4 |
_aIsocitrate Dehydrogenase _xantagonists & inhibitors |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aMolecular Conformation |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 | _aMolecular Dynamics Simulation |
650 | 0 | 4 | _aMutant Proteins |
650 | 0 | 4 | _aProtein Binding |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 | _aSubstrate Specificity |
650 | 0 | 4 | _aXenograft Model Antitumor Assays |
700 | 1 | _aSun, Weiguang | |
700 | 1 | _aGao, Suyu | |
700 | 1 | _aLuan, Shanshan | |
700 | 1 | _aLi, Dan | |
700 | 1 | _aChen, Renqi | |
700 | 1 | _aZhang, Qian | |
700 | 1 | _aChen, Lixia | |
700 | 1 | _aHuang, Jiangeng | |
700 | 1 | _aLi, Hua | |
773 | 0 |
_tOncotarget _gvol. 8 _gno. 27 _gp. 44255-44265 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.18632/oncotarget.17464 _zAvailable from publisher's website |
999 |
_c27168044 _d27168044 |