000 01645 a2200421 4500
005 20250517152047.0
264 0 _c20180308
008 201803s 0 0 eng d
022 _a1876-4479
024 7 _a10.1093/ecco-jcc/jjw191
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMarafini, Irene
245 0 0 _aCCL20 Is Negatively Regulated by TGF-β1 in Intestinal Epithelial Cells and Reduced in Crohn's Disease Patients With a Successful Response to Mongersen, a Smad7 Antisense Oligonucleotide.
_h[electronic resource]
260 _bJournal of Crohn's & colitis
_cMay 2017
300 _a603-609 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
650 0 4 _aCell Line
650 0 4 _aChemokine CCL20
_xblood
650 0 4 _aCrohn Disease
_xdrug therapy
650 0 4 _aDouble-Blind Method
650 0 4 _aHumans
650 0 4 _aIntestinal Mucosa
_xdrug effects
650 0 4 _aOligonucleotides
_xtherapeutic use
650 0 4 _aSmad7 Protein
_xantagonists & inhibitors
650 0 4 _aTransforming Growth Factor beta1
_xmetabolism
650 0 4 _aTreatment Outcome
700 1 _aMonteleone, Ivan
700 1 _aDinallo, Vincenzo
700 1 _aDi Fusco, Davide
700 1 _aDe Simone, Veronica
700 1 _aLaudisi, Federica
700 1 _aFantini, Massimo Claudio
700 1 _aDi Sabatino, Antonio
700 1 _aPallone, Francesco
700 1 _aMonteleone, Giovanni
773 0 _tJournal of Crohn's & colitis
_gvol. 11
_gno. 5
_gp. 603-609
856 4 0 _uhttps://doi.org/10.1093/ecco-jcc/jjw191
_zAvailable from publisher's website
999 _c27123986
_d27123986