000 02393 a2200673 4500
005 20250517151714.0
264 0 _c20170911
008 201709s 0 0 eng d
022 _a1097-0142
024 7 _a10.1002/cncr.30736
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMoore, Kathleen N
245 0 0 _aPhase 1 dose-escalation study of mirvetuximab soravtansine (IMGN853), a folate receptor α-targeting antibody-drug conjugate, in patients with solid tumors.
_h[electronic resource]
260 _bCancer
_cAug 2017
300 _a3080-3087 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntibodies, Monoclonal, Humanized
_xtherapeutic use
650 0 4 _aAntineoplastic Agents
_xtherapeutic use
650 0 4 _aCarcinoma, Non-Small-Cell Lung
_xdrug therapy
650 0 4 _aCarcinoma, Ovarian Epithelial
650 0 4 _aCarcinoma, Renal Cell
_xdrug therapy
650 0 4 _aDiarrhea
_xchemically induced
650 0 4 _aDisease Progression
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aEndometrial Neoplasms
_xdrug therapy
650 0 4 _aFatigue
_xchemically induced
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aHypophosphatemia
_xchemically induced
650 0 4 _aImmunoconjugates
_xtherapeutic use
650 0 4 _aKeratitis
_xchemically induced
650 0 4 _aKidney Neoplasms
_xdrug therapy
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMaximum Tolerated Dose
650 0 4 _aMaytansine
_xanalogs & derivatives
650 0 4 _aMiddle Aged
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aNeoplasms, Glandular and Epithelial
_xdrug therapy
650 0 4 _aOvarian Neoplasms
_xdrug therapy
650 0 4 _aVision Disorders
_xchemically induced
700 1 _aBorghaei, Hossein
700 1 _aO'Malley, David M
700 1 _aJeong, Woondong
700 1 _aSeward, Shelly M
700 1 _aBauer, Todd M
700 1 _aPerez, Raymond P
700 1 _aMatulonis, Ursula A
700 1 _aRunning, Kelli L
700 1 _aZhang, Xiaoyan
700 1 _aPonte, Jose F
700 1 _aRuiz-Soto, Rodrigo
700 1 _aBirrer, Michael J
773 0 _tCancer
_gvol. 123
_gno. 16
_gp. 3080-3087
856 4 0 _uhttps://doi.org/10.1002/cncr.30736
_zAvailable from publisher's website
999 _c27111546
_d27111546