000 | 02075 a2200637 4500 | ||
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005 | 20250517150943.0 | ||
264 | 0 | _c20171219 | |
008 | 201712s 0 0 eng d | ||
022 | _a1464-3405 | ||
024 | 7 |
_a10.1016/j.bmcl.2017.04.021 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aHoyt, Scott B | |
245 | 0 | 0 |
_aDiscovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertension. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry letters _c06 2017 |
||
300 |
_a2384-2388 p. _bdigital |
||
500 | _aPublication Type: Journal Article | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntihypertensive Agents _xchemical synthesis |
650 | 0 | 4 |
_aAromatase Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 | _aCricetulus |
650 | 0 | 4 |
_aCytochrome P-450 CYP11B2 _xantagonists & inhibitors |
650 | 0 | 4 |
_aCytochrome P-450 CYP2D6 Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aHypertension _xdrug therapy |
650 | 0 | 4 |
_aIndazoles _xchemical synthesis |
650 | 0 | 4 | _aMacaca mulatta |
650 | 0 | 4 | _aMale |
650 | 0 | 4 | _aRats, Sprague-Dawley |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 |
_aSteroid 11-beta-Hydroxylase _xantagonists & inhibitors |
700 | 1 | _aTaylor, Jerry | |
700 | 1 | _aLondon, Clare | |
700 | 1 | _aAli, Amjad | |
700 | 1 | _aUjjainwalla, Feroze | |
700 | 1 | _aTata, Jim | |
700 | 1 | _aStruthers, Mary | |
700 | 1 | _aCully, Doris | |
700 | 1 | _aWisniewski, Tom | |
700 | 1 | _aRen, Ning | |
700 | 1 | _aBopp, Charlene | |
700 | 1 | _aSok, Andrea | |
700 | 1 | _aVerras, Andreas | |
700 | 1 | _aMcMasters, Daniel | |
700 | 1 | _aChen, Qing | |
700 | 1 | _aTung, Elaine | |
700 | 1 | _aTang, Wei | |
700 | 1 | _aSalituro, Gino | |
700 | 1 | _aClemas, Joe | |
700 | 1 | _aZhou, Gaochao | |
700 | 1 | _aMacNeil, Douglas | |
700 | 1 | _aDuffy, Ruth | |
700 | 1 | _aXiong, Yusheng | |
773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 27 _gno. 11 _gp. 2384-2388 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2017.04.021 _zAvailable from publisher's website |
999 |
_c27087498 _d27087498 |