000			02164 a2200649 4500
005			20250517145835.0
264		0	_c20180627
008			201806s 0 0 eng d
022			_a1523-5866
024	7		_a10.1093/neuonc/nox044 _2doi
040			_aNLM _beng _cNLM
100	1		_aMcNeill, Robert S
245	0	0	_aCombination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma. _h[electronic resource]
260			_bNeuro-oncology _cOct 2017
300			_a1469-1480 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aBrain Neoplasms _xdrug therapy
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDrug Resistance, Neoplasm
650	0	4	_aDrug Synergism
650	0	4	_aGlioblastoma _xdrug therapy
650	0	4	_aHumans
650	0	4	_aMice
650	0	4	_aMitogen-Activated Protein Kinases _xantagonists & inhibitors
650	0	4	_aPhosphoinositide-3 Kinase Inhibitors
650	0	4	_aPhosphorylation
650	0	4	_aProtein Kinase Inhibitors _xpharmacology
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aTumor Cells, Cultured
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aCanoutas, Demitra A
700	1		_aStuhlmiller, Timothy J
700	1		_aDhruv, Harshil D
700	1		_aIrvin, David M
700	1		_aBash, Ryan E
700	1		_aAngus, Steven P
700	1		_aHerring, Laura E
700	1		_aSimon, Jeremy M
700	1		_aSkinner, Kasey R
700	1		_aLimas, Juanita C
700	1		_aChen, Xin
700	1		_aSchmid, Ralf S
700	1		_aSiegel, Marni B
700	1		_aVan Swearingen, Amanda E D
700	1		_aHadler, Michael J
700	1		_aSulman, Erik P
700	1		_aSarkaria, Jann N
700	1		_aAnders, Carey K
700	1		_aGraves, Lee M
700	1		_aBerens, Michael E
700	1		_aJohnson, Gary L
700	1		_aMiller, C Ryan
773	0		_tNeuro-oncology _gvol. 19 _gno. 11 _gp. 1469-1480
856	4	0	_uhttps://doi.org/10.1093/neuonc/nox044 _zAvailable from publisher's website
999			_c27051649 _d27051649