000 02318 a2200661 4500
005 20250517144719.0
264 0 _c20181002
008 201810s 0 0 eng d
022 _a1873-4995
024 7 _a10.1016/j.jconrel.2017.03.038
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhu, Xiandi
245 0 0 _aMastocarcinoma therapy synergistically promoted by lysosome dependent apoptosis specifically evoked by 5-Fu@nanogel system with passive targeting and pH activatable dual function.
_h[electronic resource]
260 _bJournal of controlled release : official journal of the Controlled Release Society
_c05 2017
300 _a107-118 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCaspase 9
_xmetabolism
650 0 4 _aCathepsin B
_xmetabolism
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Membrane Permeability
650 0 4 _aCytochromes c
_xmetabolism
650 0 4 _aDrug Carriers
650 0 4 _aFemale
650 0 4 _aFluorouracil
_xadministration & dosage
650 0 4 _aGels
650 0 4 _aHumans
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aImines
_xchemistry
650 0 4 _aLysosomes
_xmetabolism
650 0 4 _aMembrane Potential, Mitochondrial
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Nude
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aNanostructures
_xchemistry
650 0 4 _aParticle Size
650 0 4 _aPolyethylenes
_xchemistry
700 1 _aSun, Yn
700 1 _aChen, Di
700 1 _aLi, Jingfeng
700 1 _aDong, Xia
700 1 _aWang, Jie
700 1 _aChen, Huaiwen
700 1 _aWang, Ying
700 1 _aZhang, Fulei
700 1 _aDai, Jinaxin
700 1 _aPirraco, Rogério P
700 1 _aGuo, Shangjing
700 1 _aMarques, Alexandra P
700 1 _aReis, Rui L
700 1 _aLi, Wei
773 0 _tJournal of controlled release : official journal of the Controlled Release Society
_gvol. 254
_gp. 107-118
856 4 0 _uhttps://doi.org/10.1016/j.jconrel.2017.03.038
_zAvailable from publisher's website
999 _c27016028
_d27016028