000 02031 a2200601 4500
005 20250517142541.0
264 0 _c20170828
008 201708s 0 0 eng d
022 _a1420-9071
024 7 _a10.1007/s00018-017-2494-0
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKazi, Julhash U
245 0 0 _aTyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.
_h[electronic resource]
260 _bCellular and molecular life sciences : CMLS
_c07 2017
300 _a2679-2688 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis
650 0 4 _aCell Line
650 0 4 _aCell Proliferation
650 0 4 _aCell Transformation, Neoplastic
_xmetabolism
650 0 4 _aDown-Regulation
650 0 4 _aEnzyme Activation
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xmetabolism
650 0 4 _aGene Duplication
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMutant Proteins
_xmetabolism
650 0 4 _aMutation
_xgenetics
650 0 4 _aMyeloid Cells
_xmetabolism
650 0 4 _aOncogenes
650 0 4 _aPhosphorylation
650 0 4 _aProtein Stability
650 0 4 _aProtein Tyrosine Phosphatase, Non-Receptor Type 11
_xmetabolism
650 0 4 _aProteolysis
650 0 4 _aSignal Transduction
650 0 4 _aTyrosine
_xmetabolism
650 0 4 _aUbiquitination
650 0 4 _afms-Like Tyrosine Kinase 3
_xchemistry
700 1 _aChougule, Rohit A
700 1 _aLi, Tianfeng
700 1 _aSu, Xianwei
700 1 _aMoharram, Sausan A
700 1 _aRupar, Kaja
700 1 _aMarhäll, Alissa
700 1 _aGazi, Mohiuddin
700 1 _aSun, Jianmin
700 1 _aZhao, Hui
700 1 _aRönnstrand, Lars
773 0 _tCellular and molecular life sciences : CMLS
_gvol. 74
_gno. 14
_gp. 2679-2688
856 4 0 _uhttps://doi.org/10.1007/s00018-017-2494-0
_zAvailable from publisher's website
999 _c26946790
_d26946790