000 01733 a2200457 4500
005 20250517142425.0
264 0 _c20170424
008 201704s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/acs.jmedchem.7b00179
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCurreli, Francesca
245 0 0 _aSynthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_c04 2017
300 _a3124-3153 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnti-HIV Agents
_xchemistry
650 0 4 _aBiomimetic Materials
_xchemistry
650 0 4 _aCD4 Antigens
_xchemistry
650 0 4 _aCell Line
650 0 4 _aCrystallography, X-Ray
650 0 4 _aHIV Envelope Protein gp120
_xchemistry
650 0 4 _aHIV Infections
_xdrug therapy
650 0 4 _aHIV-1
_xdrug effects
650 0 4 _aHumans
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aPyrroles
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aThiazoles
_xchemistry
650 0 4 _aVirus Internalization
_xdrug effects
700 1 _aKwon, Young Do
700 1 _aBelov, Dmitry S
700 1 _aRamesh, Ranjith R
700 1 _aKurkin, Alexander V
700 1 _aAltieri, Andrea
700 1 _aKwong, Peter D
700 1 _aDebnath, Asim K
773 0 _tJournal of medicinal chemistry
_gvol. 60
_gno. 7
_gp. 3124-3153
856 4 0 _uhttps://doi.org/10.1021/acs.jmedchem.7b00179
_zAvailable from publisher's website
999 _c26942543
_d26942543