000			01956 a2200565 4500
005			20250517142131.0
264		0	_c20170424
008			201704s 0 0 eng d
022			_a1520-4804
024	7		_a10.1021/acs.jmedchem.7b00124 _2doi
040			_aNLM _beng _cNLM
100	1		_aGopalsamy, Ariamala
245	0	0	_aDesign of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA). _h[electronic resource]
260			_bJournal of medicinal chemistry _c04 2017
300			_a3094-3108 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aDisease Models, Animal
650	0	4	_aDrug Design
650	0	4	_aEndoribonucleases _xantagonists & inhibitors
650	0	4	_aEnzyme Inhibitors _xchemistry
650	0	4	_aHEK293 Cells
650	0	4	_aHumans
650	0	4	_aMice
650	0	4	_aMolecular Docking Simulation
650	0	4	_aMuscular Atrophy, Spinal _xdrug therapy
650	0	4	_aQuinazolines _xchemistry
650	0	4	_aRNA, Messenger _xantagonists & inhibitors
650	0	4	_aSurvival of Motor Neuron 2 Protein
700	1		_aNarayanan, Arjun
700	1		_aLiu, Shenping
700	1		_aParikh, Mihir D
700	1		_aKyne, Robert E
700	1		_aFadeyi, Olugbeminiyi
700	1		_aTones, Michael A
700	1		_aCherry, Jonathan J
700	1		_aNabhan, Joseph F
700	1		_aLaRosa, Gregory
700	1		_aPetersen, Donna N
700	1		_aMenard, Carol
700	1		_aFoley, Timothy L
700	1		_aNoell, Stephen
700	1		_aRen, Yong
700	1		_aLoria, Paula M
700	1		_aMaglich-Goodwin, Jodi
700	1		_aRong, Haojing
700	1		_aJones, Lyn H
773	0		_tJournal of medicinal chemistry _gvol. 60 _gno. 7 _gp. 3094-3108
856	4	0	_uhttps://doi.org/10.1021/acs.jmedchem.7b00124 _zAvailable from publisher's website
999			_c26933043 _d26933043