000 02184 a2200601 4500
005 20250517140758.0
264 0 _c20170814
008 201708s 0 0 eng d
022 _a1468-2060
024 7 _a10.1136/annrheumdis-2016-210189
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMaier, Christiane
245 0 0 _aInhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages.
_h[electronic resource]
260 _bAnnals of the rheumatic diseases
_cJun 2017
300 _a1133-1141 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aBleomycin
650 0 4 _aCell Differentiation
_xdrug effects
650 0 4 _aCollagen
_xmetabolism
650 0 4 _aCyclic Nucleotide Phosphodiesterases, Type 4
_xmetabolism
650 0 4 _aCytokines
_xgenetics
650 0 4 _aDNA Topoisomerases, Type I
_ximmunology
650 0 4 _aDisease Models, Animal
650 0 4 _aFibroblasts
_xdrug effects
650 0 4 _aFibrosis
650 0 4 _aGene Expression
_xdrug effects
650 0 4 _aGraft vs Host Disease
_xcomplications
650 0 4 _aHumans
650 0 4 _aInterleukin-13
_xgenetics
650 0 4 _aInterleukin-6
_xgenetics
650 0 4 _aMacrophages
_xdrug effects
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Inbred C57BL
650 0 4 _aPhosphodiesterase 4 Inhibitors
_xpharmacology
650 0 4 _aRNA, Messenger
_xmetabolism
650 0 4 _aRolipram
_xpharmacology
650 0 4 _aScleroderma, Systemic
_xdrug therapy
650 0 4 _aSkin
_xdrug effects
650 0 4 _aThalidomide
_xanalogs & derivatives
650 0 4 _aTransforming Growth Factor beta1
_xgenetics
650 0 4 _aTransforming Growth Factor beta2
_xgenetics
700 1 _aRamming, Andreas
700 1 _aBergmann, Christina
700 1 _aWeinkam, Rita
700 1 _aKittan, Nicolai
700 1 _aSchett, Georg
700 1 _aDistler, Jörg H W
700 1 _aBeyer, Christian
773 0 _tAnnals of the rheumatic diseases
_gvol. 76
_gno. 6
_gp. 1133-1141
856 4 0 _uhttps://doi.org/10.1136/annrheumdis-2016-210189
_zAvailable from publisher's website
999 _c26888675
_d26888675