000 02188 a2200649 4500
005 20250517140539.0
264 0 _c20170613
008 201706s 0 0 eng d
022 _a1791-2423
024 7 _a10.3892/ijo.2017.3860
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJiang, Wenchun
245 0 0 _aRepositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptosis inducer in MCF-7 human breast cancer.
_h[electronic resource]
260 _bInternational journal of oncology
_cMar 2017
300 _a823-834 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xtherapeutic use
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBcl-2-Like Protein 11
_xgenetics
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCarbamates
_xtherapeutic use
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aDrug Repositioning
_xmethods
650 0 4 _aFemale
650 0 4 _aFurans
650 0 4 _aHIV Protease Inhibitors
_xtherapeutic use
650 0 4 _aHumans
650 0 4 _aMCF-7 Cells
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Nude
650 0 4 _aMitogen-Activated Protein Kinase 1
_xantagonists & inhibitors
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Dynamics Simulation
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aRNA Interference
650 0 4 _aRNA, Small Interfering
_xgenetics
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSulfonamides
_xtherapeutic use
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aLi, Xin
700 1 _aLi, Tongyu
700 1 _aWang, Hailian
700 1 _aShi, Wei
700 1 _aQi, Ping
700 1 _aLi, Chunyang
700 1 _aChen, Jie
700 1 _aBao, Jinku
700 1 _aHuang, Guodong
700 1 _aWang, Yi
773 0 _tInternational journal of oncology
_gvol. 50
_gno. 3
_gp. 823-834
856 4 0 _uhttps://doi.org/10.3892/ijo.2017.3860
_zAvailable from publisher's website
999 _c26880452
_d26880452