000 02078 a2200589 4500
005 20250517140424.0
264 0 _c20171020
008 201710s 0 0 eng d
022 _a1479-5876
024 7 _a10.1186/s12967-017-1131-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMoon, Su-Jin
245 0 0 _aThe active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1.
_h[electronic resource]
260 _bJournal of translational medicine
_c02 2017
300 _a31 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAniline Compounds
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents
_xpharmacology
650 0 4 _aArthritis, Experimental
_xcomplications
650 0 4 _aArthritis, Rheumatoid
_xdrug therapy
650 0 4 _aCell Differentiation
_xdrug effects
650 0 4 _aCrotonates
650 0 4 _aForkhead Transcription Factors
_xmetabolism
650 0 4 _aHeme Oxygenase-1
_xmetabolism
650 0 4 _aHumans
650 0 4 _aHydroxybutyrates
_xpharmacology
650 0 4 _aInflammation
_xcomplications
650 0 4 _aIsoxazoles
_xmetabolism
650 0 4 _aJurkat Cells
650 0 4 _aLeflunomide
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Inbred C57BL
650 0 4 _aNF-E2-Related Factor 2
_xmetabolism
650 0 4 _aNitric Oxide Synthase Type II
_xmetabolism
650 0 4 _aNitriles
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSpleen
_xpathology
650 0 4 _aTh17 Cells
_xcytology
650 0 4 _aToluidines
650 0 4 _aTyrosine
_xanalogs & derivatives
700 1 _aKim, Eun-Kyung
700 1 _aJhun, Joo Yeon
700 1 _aLee, Hee Jin
700 1 _aLee, Weon Sun
700 1 _aPark, Sang-Hi
700 1 _aCho, Mi-La
700 1 _aMin, Jun-Ki
773 0 _tJournal of translational medicine
_gvol. 15
_gno. 1
_gp. 31
856 4 0 _uhttps://doi.org/10.1186/s12967-017-1131-x
_zAvailable from publisher's website
999 _c26876157
_d26876157