000 02181 a2200613 4500
005 20250517140309.0
264 0 _c20170814
008 201708s 0 0 eng d
022 _a1872-7980
024 7 _a10.1016/j.canlet.2017.01.042
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDilly, Suzanne J
245 0 0 _aA chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment.
_h[electronic resource]
260 _bCancer letters
_c05 2017
300 _a16-21 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _a17-Hydroxysteroid Dehydrogenases
_xantagonists & inhibitors
650 0 4 _a3-Hydroxyacyl CoA Dehydrogenases
_xantagonists & inhibitors
650 0 4 _aAdenocarcinoma
_xdrug therapy
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xchemistry
650 0 4 _aAntipsychotic Agents
_xchemistry
650 0 4 _aBacteriophage T7
_xgenetics
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrosophila melanogaster
_xdrug effects
650 0 4 _aDrug Compounding
650 0 4 _aDrug Repositioning
_xmethods
650 0 4 _aEnzyme Inhibitors
_xchemistry
650 0 4 _aGene Library
650 0 4 _aGenomics
_xmethods
650 0 4 _aHumans
650 0 4 _aLinoleic Acids, Conjugated
_xchemistry
650 0 4 _aMale
650 0 4 _aMice, Nude
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aProstatic Neoplasms
_xdrug therapy
650 0 4 _aProtein Conformation
650 0 4 _aRisperidone
_xchemistry
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTime Factors
650 0 4 _aTumor Burden
_xdrug effects
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aClark, Andrew J
700 1 _aMarsh, Andrew
700 1 _aMitchell, Daniel A
700 1 _aCain, Ricky
700 1 _aFishwick, Colin W G
700 1 _aTaylor, Paul C
773 0 _tCancer letters
_gvol. 393
_gp. 16-21
856 4 0 _uhttps://doi.org/10.1016/j.canlet.2017.01.042
_zAvailable from publisher's website
999 _c26871815
_d26871815