000 01496 a2200397 4500
005 20250517134009.0
264 0 _c20180101
008 201801s 0 0 eng d
022 _a1545-326X
024 7 _a10.1146/annurev-med-100415-022956
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMilewicz, Dianna M
245 0 0 _aTherapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models.
_h[electronic resource]
260 _bAnnual review of medicine
_c01 2017
300 _a51-67 p.
_bdigital
500 _aPublication Type: Journal Article; Review
650 0 4 _aAortic Dissection
_xgenetics
650 0 4 _aAngiotensin II
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aAntihypertensive Agents
_xtherapeutic use
650 0 4 _aAortic Aneurysm, Thoracic
_xgenetics
650 0 4 _aDisease Models, Animal
650 0 4 _aGenetic Predisposition to Disease
650 0 4 _aHumans
650 0 4 _aLosartan
_xtherapeutic use
650 0 4 _aMarfan Syndrome
_xgenetics
650 0 4 _aMechanoreceptors
650 0 4 _aMice
650 0 4 _aMuscle, Smooth, Vascular
_xphysiopathology
650 0 4 _aSignal Transduction
650 0 4 _aTransforming Growth Factor beta
_xmetabolism
700 1 _aPrakash, Siddharth K
700 1 _aRamirez, Francesco
773 0 _tAnnual review of medicine
_gvol. 68
_gp. 51-67
856 4 0 _uhttps://doi.org/10.1146/annurev-med-100415-022956
_zAvailable from publisher's website
999 _c26795618
_d26795618