000 | 02212 a2200613 4500 | ||
---|---|---|---|
005 | 20250517133925.0 | ||
264 | 0 | _c20180424 | |
008 | 201804s 0 0 eng d | ||
022 | _a1091-6490 | ||
024 | 7 |
_a10.1073/pnas.1618627114 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aKang, Seong Su | |
245 | 0 | 0 |
_aα-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation. _h[electronic resource] |
260 |
_bProceedings of the National Academy of Sciences of the United States of America _c01 2017 |
||
300 |
_a1183-1188 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_a1-Methyl-4-phenylpyridinium _xtoxicity |
650 | 0 | 4 |
_aAdenylate Kinase _xmetabolism |
650 | 0 | 4 | _aAged |
650 | 0 | 4 | _aAged, 80 and over |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 | _aCell Death |
650 | 0 | 4 |
_aDopaminergic Neurons _xmetabolism |
650 | 0 | 4 | _aEnzyme Activation |
650 | 0 | 4 |
_aGTP Phosphohydrolases _xdeficiency |
650 | 0 | 4 |
_aGTP-Binding Proteins _xchemistry |
650 | 0 | 4 |
_aGTPase-Activating Proteins _xchemistry |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aLewy Bodies _xmetabolism |
650 | 0 | 4 |
_aMPTP Poisoning _xmetabolism |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMice, Inbred C57BL |
650 | 0 | 4 | _aMice, Knockout |
650 | 0 | 4 |
_aNerve Tissue Proteins _xdeficiency |
650 | 0 | 4 | _aPhosphorylation |
650 | 0 | 4 | _aPleckstrin Homology Domains |
650 | 0 | 4 | _aProtein Aggregation, Pathological |
650 | 0 | 4 | _aProtein Binding |
650 | 0 | 4 | _aProtein Interaction Mapping |
650 | 0 | 4 | _aProtein Processing, Post-Translational |
650 | 0 | 4 |
_aProto-Oncogene Proteins c-fyn _xdeficiency |
650 | 0 | 4 |
_aalpha-Synuclein _xmetabolism |
700 | 1 | _aZhang, Zhentao | |
700 | 1 | _aLiu, Xia | |
700 | 1 | _aManfredsson, Fredric P | |
700 | 1 | _aHe, Li | |
700 | 1 | _aIuvone, P Michael | |
700 | 1 | _aCao, Xuebing | |
700 | 1 | _aSun, Yi E | |
700 | 1 | _aJin, Lingjing | |
700 | 1 | _aYe, Keqiang | |
773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 114 _gno. 5 _gp. 1183-1188 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.1618627114 _zAvailable from publisher's website |
999 |
_c26793005 _d26793005 |