000 02147 a2200637 4500
005 20250517132925.0
264 0 _c20170802
008 201708s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.aah4307
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMu, Ping
245 0 0 _aSOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_c01 2017
300 _a84-88 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAndrogen Antagonists
_xtherapeutic use
650 0 4 _aBenzamides
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Lineage
650 0 4 _aCell Plasticity
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aNitriles
650 0 4 _aPhenylthiohydantoin
_xanalogs & derivatives
650 0 4 _aProstatic Neoplasms
_xdrug therapy
650 0 4 _aRetinoblastoma Binding Proteins
_xgenetics
650 0 4 _aSOXB1 Transcription Factors
_xgenetics
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
650 0 4 _aUbiquitin-Protein Ligases
_xgenetics
700 1 _aZhang, Zeda
700 1 _aBenelli, Matteo
700 1 _aKarthaus, Wouter R
700 1 _aHoover, Elizabeth
700 1 _aChen, Chi-Chao
700 1 _aWongvipat, John
700 1 _aKu, Sheng-Yu
700 1 _aGao, Dong
700 1 _aCao, Zhen
700 1 _aShah, Neel
700 1 _aAdams, Elizabeth J
700 1 _aAbida, Wassim
700 1 _aWatson, Philip A
700 1 _aPrandi, Davide
700 1 _aHuang, Chun-Hao
700 1 _ade Stanchina, Elisa
700 1 _aLowe, Scott W
700 1 _aEllis, Leigh
700 1 _aBeltran, Himisha
700 1 _aRubin, Mark A
700 1 _aGoodrich, David W
700 1 _aDemichelis, Francesca
700 1 _aSawyers, Charles L
773 0 _tScience (New York, N.Y.)
_gvol. 355
_gno. 6320
_gp. 84-88
856 4 0 _uhttps://doi.org/10.1126/science.aah4307
_zAvailable from publisher's website
999 _c26758984
_d26758984