000 01808 a2200493 4500
005 20250517131505.0
264 0 _c20180221
008 201802s 0 0 eng d
022 _a1521-009X
024 7 _a10.1124/dmd.116.071613
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLiu, Hong
245 0 0 _aMetabolism and Disposition of a Novel B-Cell Lymphoma-2 Inhibitor Venetoclax in Humans and Characterization of Its Unusual Metabolites.
_h[electronic resource]
260 _bDrug metabolism and disposition: the biological fate of chemicals
_c03 2017
300 _a294-305 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAbsorption, Physiological
650 0 4 _aAdministration, Oral
650 0 4 _aAntineoplastic Agents
_xblood
650 0 4 _aBiotransformation
650 0 4 _aBridged Bicyclo Compounds, Heterocyclic
_xblood
650 0 4 _aFeces
_xchemistry
650 0 4 _aFemale
650 0 4 _aHealthy Volunteers
650 0 4 _aHumans
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xantagonists & inhibitors
650 0 4 _aSulfonamides
_xblood
650 0 4 _aTissue Distribution
700 1 _aMichmerhuizen, Melissa J
700 1 _aLao, Yanbin
700 1 _aWan, Katty
700 1 _aSalem, Ahmed Hamed
700 1 _aSawicki, James
700 1 _aSerby, Michael
700 1 _aVaidyanathan, Srirajan
700 1 _aWong, Shekman L
700 1 _aAgarwal, Suresh
700 1 _aDunbar, Martin
700 1 _aSydor, Jens
700 1 _ade Morais, Sonia M
700 1 _aLee, Anthony J
773 0 _tDrug metabolism and disposition: the biological fate of chemicals
_gvol. 45
_gno. 3
_gp. 294-305
856 4 0 _uhttps://doi.org/10.1124/dmd.116.071613
_zAvailable from publisher's website
999 _c26712938
_d26712938