000 01868 a2200493 4500
005 20250517130644.0
264 0 _c20170726
008 201707s 0 0 eng d
022 _a1879-3177
024 7 _a10.1016/j.tiv.2016.12.002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Ming
245 0 0 _aThe consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
_h[electronic resource]
260 _bToxicology in vitro : an international journal published in association with BIBRA
_cApr 2017
300 _a26-33 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aATP Binding Cassette Transporter, Subfamily B, Member 1
_xantagonists & inhibitors
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aColon
_xmetabolism
650 0 4 _aCyclosporins
_xpharmacology
650 0 4 _aCytochrome P-450 CYP3A
_xmetabolism
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
_xpharmacology
650 0 4 _aDrug Interactions
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aIleum
_xmetabolism
650 0 4 _aIn Vitro Techniques
650 0 4 _aIsoquinolines
_xpharmacology
650 0 4 _aJejunum
_xmetabolism
650 0 4 _aKetoconazole
_xpharmacology
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aQuinazolines
_xpharmacology
650 0 4 _aQuinidine
_xanalogs & derivatives
650 0 4 _aVerapamil
_xpharmacology
700 1 _ade Graaf, Inge A M
700 1 _avan de Steeg, Evita
700 1 _ade Jager, Marina H
700 1 _aGroothuis, Geny M M
773 0 _tToxicology in vitro : an international journal published in association with BIBRA
_gvol. 40
_gp. 26-33
856 4 0 _uhttps://doi.org/10.1016/j.tiv.2016.12.002
_zAvailable from publisher's website
999 _c26685338
_d26685338