000 02143 a2200661 4500
005 20250517130428.0
264 0 _c20171128
008 201711s 0 0 eng d
022 _a1942-0870
024 7 _a10.1080/19420862.2016.1268305
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDing, Kun
245 0 0 _aGeneration and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration.
_h[electronic resource]
260 _bmAbs
_c
300 _a269-284 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAngiogenesis Inhibitors
_xpharmacology
650 0 4 _aAnimals
650 0 4 _aAntibodies, Bispecific
_xpharmacology
650 0 4 _aBecaplermin
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMacular Degeneration
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aProtein Engineering
650 0 4 _aProto-Oncogene Proteins c-sis
_xantagonists & inhibitors
650 0 4 _aRabbits
650 0 4 _aVascular Endothelial Growth Factor A
_xantagonists & inhibitors
700 1 _aEaton, Lucia
700 1 _aBowley, Diana
700 1 _aRieser, Matthew
700 1 _aChang, Qing
700 1 _aHarris, Maria C
700 1 _aClabbers, Anca
700 1 _aDong, Feng
700 1 _aShen, Jikui
700 1 _aHackett, Sean F
700 1 _aTouw, Debra S
700 1 _aBixby, Jacqueline
700 1 _aZhong, Suju
700 1 _aBenatuil, Lorenzo
700 1 _aBose, Sahana
700 1 _aGrinnell, Christine
700 1 _aPreston, Gregory M
700 1 _aIyer, Ramesh
700 1 _aSadhukhan, Ramkrishna
700 1 _aMarchie, Susan
700 1 _aOvermeyer, Gary
700 1 _aGhayur, Tariq
700 1 _avan Riet, Deborah A
700 1 _aTang, Shibo
700 1 _aCampochario, Peter A
700 1 _aGu, Jijie
773 0 _tmAbs
_gvol. 9
_gno. 2
_gp. 269-284
856 4 0 _uhttps://doi.org/10.1080/19420862.2016.1268305
_zAvailable from publisher's website
999 _c26677195
_d26677195