000 01867 a2200541 4500
005 20250517130132.0
264 0 _c20170906
008 201709s 0 0 eng d
022 _a1558-8238
024 7 _a10.1172/JCI84262
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCao, Juxiang
245 0 0 _aTuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation.
_h[electronic resource]
260 _bThe Journal of clinical investigation
_c01 2017
300 _a349-364 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdolescent
650 0 4 _aAdult
650 0 4 _aAlleles
650 0 4 _aCell Line, Tumor
650 0 4 _aFemale
650 0 4 _aGlycogen Synthase Kinase 3 beta
_xgenetics
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMechanistic Target of Rapamycin Complex 1
650 0 4 _aMelanins
_xbiosynthesis
650 0 4 _aMelanocytes
_xmetabolism
650 0 4 _aMicrophthalmia-Associated Transcription Factor
_xgenetics
650 0 4 _aMiddle Aged
650 0 4 _aMultiprotein Complexes
_xgenetics
650 0 4 _aMutation
650 0 4 _aProto-Oncogene Proteins c-akt
_xgenetics
650 0 4 _aSignal Transduction
650 0 4 _aSkin Pigmentation
650 0 4 _aTOR Serine-Threonine Kinases
_xgenetics
650 0 4 _aTuberous Sclerosis
_xgenetics
650 0 4 _aTuberous Sclerosis Complex 1 Protein
650 0 4 _aTuberous Sclerosis Complex 2 Protein
650 0 4 _aTumor Suppressor Proteins
_xgenetics
650 0 4 _abeta Catenin
_xgenetics
700 1 _aTyburczy, Magdalena E
700 1 _aMoss, Joel
700 1 _aDarling, Thomas N
700 1 _aWidlund, Hans R
700 1 _aKwiatkowski, David J
773 0 _tThe Journal of clinical investigation
_gvol. 127
_gno. 1
_gp. 349-364
856 4 0 _uhttps://doi.org/10.1172/JCI84262
_zAvailable from publisher's website
999 _c26667129
_d26667129