000 01497 a2200397 4500
005 20250517125403.0
264 0 _c20181211
008 201812s 0 0 eng d
022 _a0925-4439
024 7 _a10.1016/j.bbadis.2016.11.022
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHu, Ji-Ying
245 0 0 _aPathological concentration of zinc dramatically accelerates abnormal aggregation of full-length human Tau and thereby significantly increases Tau toxicity in neuronal cells.
_h[electronic resource]
260 _bBiochimica et biophysica acta. Molecular basis of disease
_c02 2017
300 _a414-427 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlzheimer Disease
_xmetabolism
650 0 4 _aApoptosis
650 0 4 _aCations, Divalent
_xmetabolism
650 0 4 _aCell Line
650 0 4 _aHumans
650 0 4 _aNeurons
_xmetabolism
650 0 4 _aProtein Aggregates
650 0 4 _aProtein Aggregation, Pathological
_xmetabolism
650 0 4 _aZinc
_xmetabolism
650 0 4 _atau Proteins
_xmetabolism
700 1 _aZhang, De-Lin
700 1 _aLiu, Xiao-Ling
700 1 _aLi, Xue-Shou
700 1 _aCheng, Xiao-Qing
700 1 _aChen, Jie
700 1 _aDu, Hai-Ning
700 1 _aLiang, Yi
773 0 _tBiochimica et biophysica acta. Molecular basis of disease
_gvol. 1863
_gno. 2
_gp. 414-427
856 4 0 _uhttps://doi.org/10.1016/j.bbadis.2016.11.022
_zAvailable from publisher's website
999 _c26643062
_d26643062