000 02048 a2200529 4500
005 20250517124830.0
264 0 _c20190103
008 201901s 0 0 eng d
022 _a1423-0194
024 7 _a10.1159/000453369
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aReuther, Clemens
245 0 0 _aThe HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1.
_h[electronic resource]
260 _bNeuroendocrinology
_c2018
300 _a1-19 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCyclin-Dependent Kinase Inhibitor p21
_xmetabolism
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aDrug Therapy, Combination
650 0 4 _aE2F1 Transcription Factor
_xmetabolism
650 0 4 _aFluorouracil
_xpharmacology
650 0 4 _aHumans
650 0 4 _aIsoquinolines
_xpharmacology
650 0 4 _aNeuroendocrine Tumors
_xdrug therapy
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xantagonists & inhibitors
650 0 4 _aRetinoblastoma Protein
_xmetabolism
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aHeinzle, Vera
700 1 _aNölting, Svenja
700 1 _aHerterich, Sabine
700 1 _aHahner, Stefanie
700 1 _aHalilovic, Ensar
700 1 _aJeay, Sébastien
700 1 _aWuerthner, Jens U
700 1 _aAristizabal Prada, Elke Tatjana
700 1 _aSpöttl, Gerald
700 1 _aMaurer, Julian
700 1 _aAuernhammer, Christoph J
773 0 _tNeuroendocrinology
_gvol. 106
_gno. 1
_gp. 1-19
856 4 0 _uhttps://doi.org/10.1159/000453369
_zAvailable from publisher's website
999 _c26625979
_d26625979