000 01384 a2200361 4500
005 20250517124549.0
264 0 _c20171116
008 201711s 0 0 eng d
022 _a1545-4304
024 7 _a10.1146/annurev-pharmtox-010716-104837
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aColeman, Paul J
245 0 0 _aThe Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia.
_h[electronic resource]
260 _bAnnual review of pharmacology and toxicology
_c01 2017
300 _a509-533 p.
_bdigital
500 _aPublication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAzepines
_xchemistry
650 0 4 _aDrug Discovery
_xmethods
650 0 4 _aHumans
650 0 4 _aOrexin Receptor Antagonists
_xchemistry
650 0 4 _aOrexin Receptors
_xchemistry
650 0 4 _aProtein Structure, Secondary
650 0 4 _aSleep Aids, Pharmaceutical
_xchemistry
650 0 4 _aSleep Initiation and Maintenance Disorders
_xdrug therapy
650 0 4 _aTriazoles
_xchemistry
700 1 _aGotter, Anthony L
700 1 _aHerring, W Joseph
700 1 _aWinrow, Christopher J
700 1 _aRenger, John J
773 0 _tAnnual review of pharmacology and toxicology
_gvol. 57
_gp. 509-533
856 4 0 _uhttps://doi.org/10.1146/annurev-pharmtox-010716-104837
_zAvailable from publisher's website
999 _c26616681
_d26616681