000 | 02212 a2200709 4500 | ||
---|---|---|---|
005 | 20250517123559.0 | ||
264 | 0 | _c20170321 | |
008 | 201703s 0 0 eng d | ||
022 | _a1476-4687 | ||
024 | 7 |
_a10.1038/nature20134 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aDever, Daniel P | |
245 | 0 | 0 |
_aCRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells. _h[electronic resource] |
260 |
_bNature _c11 2016 |
||
300 |
_a384-389 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAlleles |
650 | 0 | 4 |
_aAnemia, Sickle Cell _xgenetics |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAntigens, CD34 _xmetabolism |
650 | 0 | 4 |
_aCRISPR-Associated Proteins _xmetabolism |
650 | 0 | 4 |
_aCRISPR-Cas Systems _xgenetics |
650 | 0 | 4 | _aCell Differentiation |
650 | 0 | 4 | _aCell Lineage |
650 | 0 | 4 | _aCell Separation |
650 | 0 | 4 |
_aDependovirus _xgenetics |
650 | 0 | 4 | _aErythrocytes |
650 | 0 | 4 | _aFemale |
650 | 0 | 4 | _aFlow Cytometry |
650 | 0 | 4 |
_aGene Editing _xmethods |
650 | 0 | 4 | _aGene Targeting |
650 | 0 | 4 | _aGenes, Reporter |
650 | 0 | 4 |
_aGenetic Therapy _xmethods |
650 | 0 | 4 |
_aHematopoietic Stem Cells _xmetabolism |
650 | 0 | 4 | _aHomologous Recombination |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMagnets |
650 | 0 | 4 | _aMice, Inbred NOD |
650 | 0 | 4 | _aMice, SCID |
650 | 0 | 4 | _aMicrospheres |
650 | 0 | 4 | _aMutation |
650 | 0 | 4 |
_aRNA, Messenger _xbiosynthesis |
650 | 0 | 4 |
_abeta-Globins _xgenetics |
650 | 0 | 4 |
_abeta-Thalassemia _xgenetics |
700 | 1 | _aBak, Rasmus O | |
700 | 1 | _aReinisch, Andreas | |
700 | 1 | _aCamarena, Joab | |
700 | 1 | _aWashington, Gabriel | |
700 | 1 | _aNicolas, Carmencita E | |
700 | 1 | _aPavel-Dinu, Mara | |
700 | 1 | _aSaxena, Nivi | |
700 | 1 | _aWilkens, Alec B | |
700 | 1 | _aMantri, Sruthi | |
700 | 1 | _aUchida, Nobuko | |
700 | 1 | _aHendel, Ayal | |
700 | 1 | _aNarla, Anupama | |
700 | 1 | _aMajeti, Ravindra | |
700 | 1 | _aWeinberg, Kenneth I | |
700 | 1 | _aPorteus, Matthew H | |
773 | 0 |
_tNature _gvol. 539 _gno. 7629 _gp. 384-389 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/nature20134 _zAvailable from publisher's website |
999 |
_c26583729 _d26583729 |