000 02597 a2200757 4500
005 20250517123518.0
264 0 _c20170313
008 201703s 0 0 eng d
022 _a1096-0295
024 7 _a10.1016/j.yrtph.2016.11.004
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aOviedo, Alberto
245 0 0 _aEvaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.
_h[electronic resource]
260 _bRegulatory toxicology and pharmacology : RTP
_cNov 2016
300 _aS93-S122 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAerosols
650 0 4 _aAnimals
650 0 4 _aBiomarkers
_xblood
650 0 4 _aComputational Biology
650 0 4 _aConsumer Product Safety
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aElectronic Nicotine Delivery Systems
_xadverse effects
650 0 4 _aEquipment Design
650 0 4 _aFemale
650 0 4 _aGene Expression Profiling
650 0 4 _aGene Expression Regulation
_xdrug effects
650 0 4 _aGenetic Markers
650 0 4 _aGenomics
650 0 4 _aHarm Reduction
650 0 4 _aHot Temperature
650 0 4 _aHumans
650 0 4 _aInhalation Exposure
_xadverse effects
650 0 4 _aLung
_xdrug effects
650 0 4 _aMale
650 0 4 _aMenthol
_xanalysis
650 0 4 _aNasal Mucosa
_xdrug effects
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aRisk Assessment
650 0 4 _aSmoke
_xadverse effects
650 0 4 _aSmoking
_xadverse effects
650 0 4 _aTime Factors
650 0 4 _aTobacco Industry
650 0 4 _aTobacco Products
_xanalysis
650 0 4 _aToxicity Tests
_xmethods
650 0 4 _aToxicogenetics
650 0 4 _aTranscriptome
_xdrug effects
700 1 _aLebrun, Stefan
700 1 _aKogel, Ulrike
700 1 _aHo, Jenny
700 1 _aTan, Wei Teck
700 1 _aTitz, Bjoern
700 1 _aLeroy, Patrice
700 1 _aVuillaume, Gregory
700 1 _aBera, Monali
700 1 _aMartin, Florian
700 1 _aRodrigo, Gregory
700 1 _aEsposito, Marco
700 1 _aDempsey, Ruth
700 1 _aIvanov, Nikolai V
700 1 _aHoeng, Julia
700 1 _aPeitsch, Manuel C
700 1 _aVanscheeuwijck, Patrick
773 0 _tRegulatory toxicology and pharmacology : RTP
_gvol. 81 Suppl 2
_gp. S93-S122
856 4 0 _uhttps://doi.org/10.1016/j.yrtph.2016.11.004
_zAvailable from publisher's website
999 _c26581300
_d26581300