000 | 02366 a2200709 4500 | ||
---|---|---|---|
005 | 20250517123015.0 | ||
264 | 0 | _c20170321 | |
008 | 201703s 0 0 eng d | ||
022 | _a1476-4687 | ||
024 | 7 |
_a10.1038/nature20132 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aKottakis, Filippos | |
245 | 0 | 0 |
_aLKB1 loss links serine metabolism to DNA methylation and tumorigenesis. _h[electronic resource] |
260 |
_bNature _c11 2016 |
||
300 |
_a390-395 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAMP-Activated Protein Kinase Kinases |
650 | 0 | 4 | _aAMP-Activated Protein Kinases |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 | _aCell Culture Techniques |
650 | 0 | 4 | _aCell Line, Tumor |
650 | 0 | 4 | _aCell Transformation, Neoplastic |
650 | 0 | 4 |
_aChromatin _xgenetics |
650 | 0 | 4 |
_aDNA (Cytosine-5-)-Methyltransferases _xmetabolism |
650 | 0 | 4 |
_aDNA Methylation _xdrug effects |
650 | 0 | 4 |
_aEnzyme Inhibitors _xpharmacology |
650 | 0 | 4 |
_aEpithelial Cells _xmetabolism |
650 | 0 | 4 | _aGene Silencing |
650 | 0 | 4 | _aGenes, Tumor Suppressor |
650 | 0 | 4 |
_aGlycine _xmetabolism |
650 | 0 | 4 | _aGlycolysis |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMice |
650 | 0 | 4 |
_aPancreatic Ducts _xcytology |
650 | 0 | 4 |
_aProtein Serine-Threonine Kinases _xdeficiency |
650 | 0 | 4 |
_aProto-Oncogene Proteins p21(ras) _xgenetics |
650 | 0 | 4 |
_aRetroelements _xgenetics |
650 | 0 | 4 |
_aS-Adenosylmethionine _xmetabolism |
650 | 0 | 4 |
_aSerine _xbiosynthesis |
650 | 0 | 4 |
_aTOR Serine-Threonine Kinases _xmetabolism |
650 | 0 | 4 |
_aTransaminases _xmetabolism |
700 | 1 | _aNicolay, Brandon N | |
700 | 1 | _aRoumane, Ahlima | |
700 | 1 | _aKarnik, Rahul | |
700 | 1 | _aGu, Hongcang | |
700 | 1 | _aNagle, Julia M | |
700 | 1 | _aBoukhali, Myriam | |
700 | 1 | _aHayward, Michele C | |
700 | 1 | _aLi, Yvonne Y | |
700 | 1 | _aChen, Ting | |
700 | 1 | _aLiesa, Marc | |
700 | 1 | _aHammerman, Peter S | |
700 | 1 | _aWong, Kwok Kin | |
700 | 1 | _aHayes, D Neil | |
700 | 1 | _aShirihai, Orian S | |
700 | 1 | _aDyson, Nicholas J | |
700 | 1 | _aHaas, Wilhelm | |
700 | 1 | _aMeissner, Alexander | |
700 | 1 | _aBardeesy, Nabeel | |
773 | 0 |
_tNature _gvol. 539 _gno. 7629 _gp. 390-395 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1038/nature20132 _zAvailable from publisher's website |
999 |
_c26565683 _d26565683 |