000 | 02779 a2200853 4500 | ||
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005 | 20250517122813.0 | ||
264 | 0 | _c20170310 | |
008 | 201703s 0 0 eng d | ||
022 | _a1554-8937 | ||
024 | 7 |
_a10.1021/acschembio.6b00677 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aTelliez, Jean-Baptiste | |
245 | 0 | 0 |
_aDiscovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition. _h[electronic resource] |
260 |
_bACS chemical biology _c12 2016 |
||
300 |
_a3442-3451 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aArthritis, Experimental _xdrug therapy |
650 | 0 | 4 | _aDisease Models, Animal |
650 | 0 | 4 | _aDrug Discovery |
650 | 0 | 4 |
_aEncephalomyelitis, Autoimmune, Experimental _xdrug therapy |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 |
_aInterleukin-10 _ximmunology |
650 | 0 | 4 |
_aInterleukin-1beta _ximmunology |
650 | 0 | 4 |
_aJanus Kinase 1 _xantagonists & inhibitors |
650 | 0 | 4 |
_aJanus Kinase 3 _xantagonists & inhibitors |
650 | 0 | 4 |
_aMacrophages _xcytology |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 |
_aProtein Kinase Inhibitors _xpharmacokinetics |
650 | 0 | 4 |
_aPyrimidines _xpharmacokinetics |
650 | 0 | 4 |
_aPyrroles _xpharmacokinetics |
650 | 0 | 4 | _aRats |
650 | 0 | 4 |
_aTh1 Cells _xcytology |
650 | 0 | 4 |
_aTh17 Cells _xcytology |
650 | 0 | 4 |
_aTumor Necrosis Factor-alpha _ximmunology |
700 | 1 | _aDowty, Martin E | |
700 | 1 | _aWang, Lu | |
700 | 1 | _aJussif, Jason | |
700 | 1 | _aLin, Tsung | |
700 | 1 | _aLi, Li | |
700 | 1 | _aMoy, Erick | |
700 | 1 | _aBalbo, Paul | |
700 | 1 | _aLi, Wei | |
700 | 1 | _aZhao, Yajuan | |
700 | 1 | _aCrouse, Kimberly | |
700 | 1 | _aDickinson, Caitlyn | |
700 | 1 | _aSymanowicz, Peter | |
700 | 1 | _aHegen, Martin | |
700 | 1 | _aBanker, Mary Ellen | |
700 | 1 | _aVincent, Fabien | |
700 | 1 | _aUnwalla, Ray | |
700 | 1 | _aLiang, Sidney | |
700 | 1 | _aGilbert, Adam M | |
700 | 1 | _aBrown, Matthew F | |
700 | 1 | _aHayward, Matthew | |
700 | 1 | _aMontgomery, Justin | |
700 | 1 | _aYang, Xin | |
700 | 1 | _aBauman, Jonathan | |
700 | 1 | _aTrujillo, John I | |
700 | 1 | _aCasimiro-Garcia, Agustin | |
700 | 1 | _aVajdos, Felix F | |
700 | 1 | _aLeung, Louis | |
700 | 1 | _aGeoghegan, Kieran F | |
700 | 1 | _aQuazi, Amira | |
700 | 1 | _aXuan, Dejun | |
700 | 1 | _aJones, Lyn | |
700 | 1 | _aHett, Erik | |
700 | 1 | _aWright, Katherine | |
700 | 1 | _aClark, James D | |
700 | 1 | _aThorarensen, Atli | |
773 | 0 |
_tACS chemical biology _gvol. 11 _gno. 12 _gp. 3442-3451 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/acschembio.6b00677 _zAvailable from publisher's website |
999 |
_c26558679 _d26558679 |