000			01997 a2200553 4500
005			20250517122022.0
264		0	_c20180416
008			201804s 0 0 eng d
022			_a2045-2322
024	7		_a10.1038/srep35294 _2doi
040			_aNLM _beng _cNLM
100	1		_aWang, Juexin
245	0	0	_aDifferential protein structural disturbances and suppression of assembly partners produced by nonsense GABRG2 epilepsy mutations: implications for disease phenotypic heterogeneity. _h[electronic resource]
260			_bScientific reports _c10 2016
300			_a35294 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aBinding Sites
650	0	4	_aCell Membrane _xmetabolism
650	0	4	_aCodon, Nonsense
650	0	4	_aEpilepsies, Myoclonic _xgenetics
650	0	4	_aEpilepsy, Absence _xgenetics
650	0	4	_aEvoked Potentials _xphysiology
650	0	4	_aGene Expression
650	0	4	_aHEK293 Cells
650	0	4	_aHumans
650	0	4	_aHydrophobic and Hydrophilic Interactions
650	0	4	_aMolecular Docking Simulation
650	0	4	_aPatch-Clamp Techniques
650	0	4	_aPhenotype
650	0	4	_aProtein Binding
650	0	4	_aProtein Conformation, alpha-Helical
650	0	4	_aProtein Conformation, beta-Strand
650	0	4	_aProtein Interaction Domains and Motifs
650	0	4	_aProtein Multimerization
650	0	4	_aProtein Subunits _xchemistry
650	0	4	_aReceptors, GABA-A _xchemistry
650	0	4	_aSeizures _xgenetics
650	0	4	_aSeverity of Illness Index
650	0	4	_aStructural Homology, Protein
650	0	4	_aTransfection
700	1		_aShen, Dingding
700	1		_aXia, Geqing
700	1		_aShen, Wangzhen
700	1		_aMacdonald, Robert L
700	1		_aXu, Dong
700	1		_aKang, Jing-Qiong
773	0		_tScientific reports _gvol. 6 _gp. 35294
856	4	0	_uhttps://doi.org/10.1038/srep35294 _zAvailable from publisher's website
999			_c26534024 _d26534024