000 02077 a2200577 4500
005 20250517121752.0
264 0 _c20180423
008 201804s 0 0 eng d
022 _a2045-2322
024 7 _a10.1038/srep35468
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aChen, Minghui
245 0 0 _aApigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner.
_h[electronic resource]
260 _bScientific reports
_c10 2016
300 _a35468 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApigenin
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCarcinoma, Non-Small-Cell Lung
_xgenetics
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDisease Models, Animal
650 0 4 _aDrug Synergism
650 0 4 _aGene Expression Regulation, Neoplastic
_xdrug effects
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xgenetics
650 0 4 _aMAP Kinase Signaling System
650 0 4 _aMice
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aNF-kappa B
_xmetabolism
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aReceptors, TNF-Related Apoptosis-Inducing Ligand
_xgenetics
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTNF-Related Apoptosis-Inducing Ligand
_xpharmacology
650 0 4 _aTumor Stem Cell Assay
650 0 4 _aTumor Suppressor Protein p53
_xmetabolism
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aWang, Xueshi
700 1 _aZha, Daolong
700 1 _aCai, Fangfang
700 1 _aZhang, Wenjing
700 1 _aHe, Yan
700 1 _aHuang, Qilai
700 1 _aZhuang, Hongqin
700 1 _aHua, Zi-Chun
773 0 _tScientific reports
_gvol. 6
_gp. 35468
856 4 0 _uhttps://doi.org/10.1038/srep35468
_zAvailable from publisher's website
999 _c26525160
_d26525160