000 01980 a2200625 4500
005 20250517121707.0
264 0 _c20170425
008 201704s 0 0 eng d
022 _a1476-5594
024 7 _a10.1038/onc.2016.382
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHarrod, A
245 0 0 _aGenomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.
_h[electronic resource]
260 _bOncogene
_c04 2017
300 _a2286-2296 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntineoplastic Agents
_xtherapeutic use
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCRISPR-Cas Systems
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCyclin-Dependent Kinases
_xantagonists & inhibitors
650 0 4 _aEstrogen Antagonists
_xpharmacology
650 0 4 _aEstrogen Receptor alpha
_xgenetics
650 0 4 _aEstrogens
_xpharmacology
650 0 4 _aFemale
650 0 4 _aGene Knock-In Techniques
650 0 4 _aHistones
_xmetabolism
650 0 4 _aHumans
650 0 4 _aMCF-7 Cells
650 0 4 _aMutation
650 0 4 _aPhosphorylation
650 0 4 _aSerine
_xmetabolism
650 0 4 _aTamoxifen
_xanalogs & derivatives
650 0 4 _aCyclin-Dependent Kinase-Activating Kinase
700 1 _aFulton, J
700 1 _aNguyen, V T M
700 1 _aPeriyasamy, M
700 1 _aRamos-Garcia, L
700 1 _aLai, C-F
700 1 _aMetodieva, G
700 1 _ade Giorgio, A
700 1 _aWilliams, R L
700 1 _aSantos, D B
700 1 _aGomez, P J
700 1 _aLin, M-L
700 1 _aMetodiev, M V
700 1 _aStebbing, J
700 1 _aCastellano, L
700 1 _aMagnani, L
700 1 _aCoombes, R C
700 1 _aBuluwela, L
700 1 _aAli, S
773 0 _tOncogene
_gvol. 36
_gno. 16
_gp. 2286-2296
856 4 0 _uhttps://doi.org/10.1038/onc.2016.382
_zAvailable from publisher's website
999 _c26522432
_d26522432