000 02050 a2200589 4500
005 20250517121618.0
264 0 _c20170928
008 201709s 0 0 eng d
022 _a1879-114X
024 7 _a10.1016/j.clinthera.2016.08.010
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDirix, Luc
245 0 0 _aEffect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies.
_h[electronic resource]
260 _bClinical therapeutics
_cOct 2016
300 _a2286-2299 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aArea Under Curve
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
_xpharmacology
650 0 4 _aCytochrome P-450 Enzyme System
_xdrug effects
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aItraconazole
_xadministration & dosage
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aPhthalazines
_xadministration & dosage
650 0 4 _aPiperazines
_xadministration & dosage
650 0 4 _aRifampin
_xadministration & dosage
700 1 _aSwaisland, Helen
700 1 _aVerheul, Henk M W
700 1 _aRottey, Sylvie
700 1 _aLeunen, Karin
700 1 _aJerusalem, Guy
700 1 _aRolfo, Christian
700 1 _aNielsen, Dorte
700 1 _aMolife, L Rhoda
700 1 _aKristeleit, Rebecca
700 1 _aVos-Geelen, Judith de
700 1 _aMau-Sørensen, Morten
700 1 _aSoetekouw, Patricia
700 1 _avan Herpen, Carla
700 1 _aFielding, Anitra
700 1 _aSo, Karen
700 1 _aBannister, Wendy
700 1 _aPlummer, Ruth
773 0 _tClinical therapeutics
_gvol. 38
_gno. 10
_gp. 2286-2299
856 4 0 _uhttps://doi.org/10.1016/j.clinthera.2016.08.010
_zAvailable from publisher's website
999 _c26519482
_d26519482