000 02227 a2200709 4500
005 20250517121500.0
264 0 _c20171009
008 201710s 0 0 eng d
022 _a1476-5551
024 7 _a10.1038/leu.2016.282
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aUy, G L
245 0 0 _aDynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.
_h[electronic resource]
260 _bLeukemia
_c04 2017
300 _a872-881 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xtherapeutic use
650 0 4 _aBone Marrow
_xpathology
650 0 4 _aClonal Evolution
_xgenetics
650 0 4 _aEpigenesis, Genetic
_xdrug effects
650 0 4 _aExome
650 0 4 _aFemale
650 0 4 _aGenes, p53
650 0 4 _aHigh-Throughput Nucleotide Sequencing
650 0 4 _aHistone Deacetylase Inhibitors
_xadministration & dosage
650 0 4 _aHumans
650 0 4 _aLeukemia, Myeloid, Acute
_xdiagnosis
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMutation
650 0 4 _aMyelodysplastic Syndromes
_xdiagnosis
650 0 4 _aPolymorphism, Single Nucleotide
650 0 4 _aRemission Induction
650 0 4 _aTreatment Outcome
650 0 4 _aTumor Burden
700 1 _aDuncavage, E J
700 1 _aChang, G S
700 1 _aJacoby, M A
700 1 _aMiller, C A
700 1 _aShao, J
700 1 _aHeath, S
700 1 _aElliott, K
700 1 _aReineck, T
700 1 _aFulton, R S
700 1 _aFronick, C C
700 1 _aO'Laughlin, M
700 1 _aGanel, L
700 1 _aAbboud, C N
700 1 _aCashen, A F
700 1 _aDiPersio, J F
700 1 _aWilson, R K
700 1 _aLink, D C
700 1 _aWelch, J S
700 1 _aLey, T J
700 1 _aGraubert, T A
700 1 _aWestervelt, P
700 1 _aWalter, M J
773 0 _tLeukemia
_gvol. 31
_gno. 4
_gp. 872-881
856 4 0 _uhttps://doi.org/10.1038/leu.2016.282
_zAvailable from publisher's website
999 _c26515060
_d26515060