| 000 | 01633 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250517121043.0 | ||
| 264 | 0 | _c20170526 | |
| 008 | 201705s 0 0 eng d | ||
| 022 | _a1548-7105 | ||
| 024 | 7 |
_a10.1038/nmeth.4027 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMa, Yunqing | |
| 245 | 0 | 0 |
_aTargeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells. _h[electronic resource] |
| 260 |
_bNature methods _cDec 2016 |
||
| 300 |
_a1029-1035 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aCRISPR-Associated Proteins _xchemistry |
| 650 | 0 | 4 | _aCell Culture Techniques |
| 650 | 0 | 4 |
_aClustered Regularly Interspaced Short Palindromic Repeats _xgenetics |
| 650 | 0 | 4 |
_aCytidine Deaminase _xchemistry |
| 650 | 0 | 4 |
_aDrug Resistance, Neoplasm _xgenetics |
| 650 | 0 | 4 |
_aFusion Proteins, bcr-abl _xgenetics |
| 650 | 0 | 4 | _aGene Targeting |
| 650 | 0 | 4 |
_aGreen Fluorescent Proteins _xchemistry |
| 650 | 0 | 4 | _aHEK293 Cells |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImatinib Mesylate _xpharmacology |
| 650 | 0 | 4 | _aK562 Cells |
| 650 | 0 | 4 | _aMutagenesis, Site-Directed |
| 650 | 0 | 4 | _aPoint Mutation |
| 650 | 0 | 4 | _aRNA, Guide, CRISPR-Cas Systems |
| 650 | 0 | 4 |
_aRecombinant Fusion Proteins _xchemistry |
| 650 | 0 | 4 | _aAICDA (Activation-Induced Cytidine Deaminase) |
| 700 | 1 | _aZhang, Jiayuan | |
| 700 | 1 | _aYin, Weijie | |
| 700 | 1 | _aZhang, Zhenchao | |
| 700 | 1 | _aSong, Yan | |
| 700 | 1 | _aChang, Xing | |
| 773 | 0 |
_tNature methods _gvol. 13 _gno. 12 _gp. 1029-1035 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/nmeth.4027 _zAvailable from publisher's website |
| 999 |
_c26501802 _d26501802 |
||