000 02637 a2200745 4500
005 20250517120805.0
264 0 _c20180223
008 201802s 0 0 eng d
022 _a1949-2553
024 7 _a10.18632/oncotarget.12428
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKashyap, Trinayan
245 0 0 _aSelinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.
_h[electronic resource]
260 _bOncotarget
_cNov 2016
300 _a78883-78895 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aActive Transport, Cell Nucleus
_xdrug effects
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xpharmacology
650 0 4 _aBone Neoplasms
_xdrug therapy
650 0 4 _aBortezomib
_xpharmacology
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Nucleus
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aDrug Synergism
650 0 4 _aFemale
650 0 4 _aFibrosarcoma
_xdrug therapy
650 0 4 _aHumans
650 0 4 _aHydrazines
_xpharmacology
650 0 4 _aKaryopherins
_xantagonists & inhibitors
650 0 4 _aMice, Inbred ICR
650 0 4 _aMice, SCID
650 0 4 _aNF-KappaB Inhibitor alpha
_xgenetics
650 0 4 _aNF-kappa B
_xgenetics
650 0 4 _aOsteosarcoma
_xdrug therapy
650 0 4 _aPhosphorylation
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProteasome Inhibitors
_xpharmacology
650 0 4 _aProteolysis
650 0 4 _aRNA Interference
650 0 4 _aReceptors, Cytoplasmic and Nuclear
_xantagonists & inhibitors
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTime Factors
650 0 4 _aTranscription Factor RelA
_xgenetics
650 0 4 _aTransfection
650 0 4 _aTriazoles
_xpharmacology
650 0 4 _aExportin 1 Protein
700 1 _aArgueta, Christian
700 1 _aAboukameel, Amro
700 1 _aUnger, Thaddeus John
700 1 _aKlebanov, Boris
700 1 _aMohammad, Ramzi M
700 1 _aMuqbil, Irfana
700 1 _aAzmi, Asfar S
700 1 _aDrolen, Claire
700 1 _aSenapedis, William
700 1 _aLee, Margaret
700 1 _aKauffman, Michael
700 1 _aShacham, Sharon
700 1 _aLandesman, Yosef
773 0 _tOncotarget
_gvol. 7
_gno. 48
_gp. 78883-78895
856 4 0 _uhttps://doi.org/10.18632/oncotarget.12428
_zAvailable from publisher's website
999 _c26492337
_d26492337