000 01561 a2200457 4500
005 20250517120248.0
264 0 _c20170727
008 201707s 0 0 eng d
022 _a1873-264X
024 7 _a10.1016/j.jpba.2016.09.040
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aShi, Fuguo
245 0 0 _aNQO1 and CYP450 reductase decrease the systemic exposure of rifampicin-quinone and mediate its redox cycle in rats.
_h[electronic resource]
260 _bJournal of pharmaceutical and biomedical analysis
_cJan 2017
300 _a17-23 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aCalibration
650 0 4 _aChromatography, Liquid
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aHep G2 Cells
650 0 4 _aHumans
650 0 4 _aLimit of Detection
650 0 4 _aMale
650 0 4 _aMass Spectrometry
650 0 4 _aNAD(P)H Dehydrogenase (Quinone)
_xmetabolism
650 0 4 _aOxidation-Reduction
650 0 4 _aQuality Control
650 0 4 _aQuinones
_xchemistry
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReproducibility of Results
650 0 4 _aRifampin
_xanalogs & derivatives
650 0 4 _aTime Factors
700 1 _aLi, Xiaobing
700 1 _aPan, Hong
700 1 _aDing, Li
773 0 _tJournal of pharmaceutical and biomedical analysis
_gvol. 132
_gp. 17-23
856 4 0 _uhttps://doi.org/10.1016/j.jpba.2016.09.040
_zAvailable from publisher's website
999 _c26475445
_d26475445