000 02172 a2200673 4500
005 20250517120019.0
264 0 _c20171211
008 201712s 0 0 eng d
022 _a1946-6242
024 7 _a10.1126/scitranslmed.aaf6812
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHiggins, Sarah J
245 0 0 _aDysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria.
_h[electronic resource]
260 _bScience translational medicine
_c09 2016
300 _a358ra128 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial
650 0 4 _aAdenoviridae
_xmetabolism
650 0 4 _aAngiopoietin-1
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aAntimalarials
_xpharmacology
650 0 4 _aArtemisinins
_xpharmacology
650 0 4 _aArtesunate
650 0 4 _aBlood-Brain Barrier
_xpathology
650 0 4 _aChild, Preschool
650 0 4 _aDisease Models, Animal
650 0 4 _aDisease Susceptibility
650 0 4 _aEndothelial Cells
_xdrug effects
650 0 4 _aFemale
650 0 4 _aGene Deletion
650 0 4 _aHumans
650 0 4 _aInfant
650 0 4 _aKaplan-Meier Estimate
650 0 4 _aKinetics
650 0 4 _aMalaria, Cerebral
_xetiology
650 0 4 _aMalaria, Falciparum
_xmetabolism
650 0 4 _aMale
650 0 4 _aMice, Inbred C57BL
650 0 4 _aPhenotype
650 0 4 _aPlasmodium falciparum
_xdrug effects
650 0 4 _aReceptor, TIE-2
_xmetabolism
650 0 4 _aRecombinant Proteins
_xpharmacology
650 0 4 _aSurvival Analysis
650 0 4 _aTreatment Outcome
650 0 4 _aUganda
700 1 _aPurcell, Lisa A
700 1 _aSilver, Karlee L
700 1 _aTran, Vanessa
700 1 _aCrowley, Valerie
700 1 _aHawkes, Michael
700 1 _aConroy, Andrea L
700 1 _aOpoka, Robert O
700 1 _aHay, John G
700 1 _aQuaggin, Susan E
700 1 _aThurston, Gavin
700 1 _aLiles, W Conrad
700 1 _aKain, Kevin C
773 0 _tScience translational medicine
_gvol. 8
_gno. 358
_gp. 358ra128
856 4 0 _uhttps://doi.org/10.1126/scitranslmed.aaf6812
_zAvailable from publisher's website
999 _c26466583
_d26466583