000 02022 a2200589 4500
005 20250517115531.0
264 0 _c20180126
008 201801s 0 0 eng d
022 _a1091-6490
024 7 _a10.1073/pnas.1612803113
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWang, Rongsheng E
245 0 0 _aRational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_c10 2016
300 _a11501-11506 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Sequence
650 0 4 _aAnimals
650 0 4 _aAntibodies, Blocking
_xpharmacology
650 0 4 _aCHO Cells
650 0 4 _aCattle
650 0 4 _aComplementarity Determining Regions
_xchemistry
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aDrug Design
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aImmunosuppressive Agents
_xpharmacology
650 0 4 _aKv1.3 Potassium Channel
_xantagonists & inhibitors
650 0 4 _aLymphocyte Activation
_xdrug effects
650 0 4 _aRats
650 0 4 _aRecombinant Fusion Proteins
_xchemistry
700 1 _aWang, Ying
700 1 _aZhang, Yuhan
700 1 _aGabrelow, Chase
700 1 _aZhang, Yong
700 1 _aChi, Victor
700 1 _aFu, Qiangwei
700 1 _aLuo, Xiaozhou
700 1 _aWang, Danling
700 1 _aJoseph, Sean
700 1 _aJohnson, Kristen
700 1 _aChatterjee, Arnab K
700 1 _aWright, Timothy M
700 1 _aNguyen-Tran, Vân T B
700 1 _aTeijaro, John
700 1 _aTheofilopoulos, Argyrios N
700 1 _aSchultz, Peter G
700 1 _aWang, Feng
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 113
_gno. 41
_gp. 11501-11506
856 4 0 _uhttps://doi.org/10.1073/pnas.1612803113
_zAvailable from publisher's website
999 _c26449904
_d26449904