000 01567 a2200397 4500
005 20250517113559.0
264 0 _c20170808
008 201708s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2016.08.036
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSola, Irene
245 0 0 _aSynthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_c11 2016
300 _a5162-5171 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAminoquinolines
_xchemical synthesis
650 0 4 _aBrain
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aMolecular Structure
650 0 4 _aParasitic Sensitivity Tests
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTrypanocidal Agents
_xchemical synthesis
650 0 4 _aTrypanosoma brucei brucei
_xdrug effects
700 1 _aArtigas, Albert
700 1 _aTaylor, Martin C
700 1 _aPérez-Areales, F Javier
700 1 _aViayna, Elisabet
700 1 _aClos, M Victòria
700 1 _aPérez, Belén
700 1 _aWright, Colin W
700 1 _aKelly, John M
700 1 _aMuñoz-Torrero, Diego
773 0 _tBioorganic & medicinal chemistry
_gvol. 24
_gno. 21
_gp. 5162-5171
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2016.08.036
_zAvailable from publisher's website
999 _c26386503
_d26386503