000 | 01567 a2200397 4500 | ||
---|---|---|---|
005 | 20250517113559.0 | ||
264 | 0 | _c20170808 | |
008 | 201708s 0 0 eng d | ||
022 | _a1464-3391 | ||
024 | 7 |
_a10.1016/j.bmc.2016.08.036 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aSola, Irene | |
245 | 0 | 0 |
_aSynthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry _c11 2016 |
||
300 |
_a5162-5171 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 |
_aAminoquinolines _xchemical synthesis |
650 | 0 | 4 |
_aBrain _xdrug effects |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 | _aMolecular Structure |
650 | 0 | 4 | _aParasitic Sensitivity Tests |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aTrypanocidal Agents _xchemical synthesis |
650 | 0 | 4 |
_aTrypanosoma brucei brucei _xdrug effects |
700 | 1 | _aArtigas, Albert | |
700 | 1 | _aTaylor, Martin C | |
700 | 1 | _aPérez-Areales, F Javier | |
700 | 1 | _aViayna, Elisabet | |
700 | 1 | _aClos, M Victòria | |
700 | 1 | _aPérez, Belén | |
700 | 1 | _aWright, Colin W | |
700 | 1 | _aKelly, John M | |
700 | 1 | _aMuñoz-Torrero, Diego | |
773 | 0 |
_tBioorganic & medicinal chemistry _gvol. 24 _gno. 21 _gp. 5162-5171 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmc.2016.08.036 _zAvailable from publisher's website |
999 |
_c26386503 _d26386503 |